Stem cells create mice

Stem cells create mice
10/01/2006 | Elhuyar
(Photo: M. Bartlett/NHGRI)

Taking advantage of sperm obtained from embryo stem cells, they have created mice at the University of Göttingen, Germany.

The natural way to create sperm is the cellular background known as spermatogony. But sterile males do not produce these cells and the team led by researcher Karim Nayernia has followed an unusual path to achieve spermatogony. The embryonic stem cells of mice have become a spermatogony from which they have obtained spermatogony.

This sperm was introduced into 210 mice eggs. Of these eggs only 65 developed, of which only seven were born. In addition, one of the seven mice born died immediately, and the remaining six presented genetic defects, their size was abnormal and died in five months. Healthy mice can live for years. Therefore, the results are not very good at the moment.

Researchers have valued the research and tried to explain the reason for these anomalies. They believe that the pattern of genes that are activated or expressed by inserting sperm into the eggs changed.

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