Transporters that can open new roads in medicine
The cell membrane should not allow the entry of external substances into the cell or allow the removal of internal substances. It can only allow the transport of specific substances, so you must use conveyors that allow the substance to cross the membrane. Bacteria, plants and humans use the ABC transporters for this work.
Researcher Geoffrey Chang has studied the three-dimensional structure of these transporters using the X-ray technique and has been published in the journal Science. This work can contribute to the fight against cancer and antibiotic-resistant bacteria.
Bacteria that have reached antibiotic resistance right now are one of the biggest health problems. In short, when we treat the infection with antibiotics, the bacteria will eliminate the antibiotics that have entered inside forming this type of transporters. Therefore, antibiotics will not die. However, bacteria are not the only ones who do, the same is true for cancer cells, which kill the drugs we use to kill them.
In short, the problem is not that there are no strong antibiotics or drugs, but that, despite entering the cell we want to die, the cells expel them. This will allow the development of other treatments, as new drugs may be generated that are taken in combination with antibiotics and chemotherapeutic agents, in order to increase the introduction and effectiveness of the former.
Zu idazle
Zientzia aldizkaria
