2016/07/14 323. zenbakia

eu es fr en cat gl

• Itzulpen automatikoa
  • Español
  • Français
  • English
  • Català
  • Galego
  • Jatorrizkora itzuli

Elia Elhuyar

×

Aparecerá un contenido traducido automáticamente. ¿Deseas continuar?

Si No

Elia Elhuyar

×

Un contenu traduit automatiquement apparaîtra. Voulez-vous continuer?

Oui No

Elia Elhuyar

×

An automatically translated content item will be displayed. Do you want to continue?

Yes No

Elia Elhuyar

×

Apareixerà un contingut traduït automàticament. Vols continuar?

Si No

Elia Elhuyar

×

Aparecerá un contido traducido automaticamente. ¿Desexas continuar?

Se No

• Farmakologia

A polymer from crustacean crustaceans is suitable for gene therapy

• Zabaldu:
• Twitter
• Facebook
• Emaila

Image of the introduction of nanoparticles in human primary neuronal cells. In blue, the nuclei of the cells; in green, the cytoskeleton of the cells; in red, the nanoparticles. Ed. Mireia Agirre/UPV

Mireia Agirre Díaz, Department of Pharmacy and Food Sciences of the UPV, has shown that an oligochessian is suitable for transporting fragments of DNA inside the cells. This oligochitosan is a natural polymer derived from the exoskeleton of crustaceans and is of low molecular weight compared to other oligochyrosane used for this purpose in gene therapy.

In his doctoral thesis, Agirre has shown that the oligochesosan adequately protects the DNA to be transported and correctly inserts it into the inside of the cell to subsequently generate the necessary protein in therapy.

In particular, Agirre has shown that oligochitosan serves two new applications: on the one hand, to influence tumor cells and on the other, to treat diseases of the central nervous system. The researcher explains that the next step is to test animals in specific applications and with therapeutic DNA. In fact, in the tests carried out so far it has been proven that it is suitable for the transport of large fragments of DNA, but this DNA was not therapeutic.